Relevant Research

Dr. Teh was the lead investigator of a project entitled “Disease characteristics, health service use and quality of life in patients with systemic lupus erythematosus in different ethnic groups” which was funded by the NHS Research and Development department from October 2000 to September 2005. The final report was published at the R&D website in 2005. Further funding was successfully applied from Lupus UK from October 2005 until September 2008. As a result of this project a Lupus specific health-related quality of life measure for adults, the LupusQoLwas developed. This has been evaluated and in 2006 copyrighted jointly to The University of Central Lancashire and East Lancashire Hospitals NHS Trust. The LupusQoL Sensitivity Study commenced on 31st January 2011 and is funded by Arthritis Research UK for 30 months.

Publications relevant to LupusQoL

• K McElhone, J Abbott, J Gray, A Williams, L-S Teh, Patient perspective of Systemic Lupus Erythematosus in relation to Health-related Quality of Life Concepts, A Qualitative Study, Lupus 2010;14:1640-7. <http://www.ncbi.nlm.nih.gov/pubmed/20709719>

• J Yazdany, Health-related quality of life measurement in adult systemic lupus erythematosus: Lupus Quality of Life (LupusQoL), Systemic Lupus Erythematosus-Specific Quality of Life Questionnaire (SLEQOL), and Systemic Lupus Erythematosus Quality of Life Questionnaire (L-QoL), Arthritis Care Res, 2011, 63: S413–S419. doi: 10.1002/acr.20636<http://www.ncbi.nlm.nih.gov/pubmed/22588761>

• K McElhone, M Castelino, J Abbott, J Shelmerdine, Y Ahmad, I Bruce, K Peers, D Isenberg, A Ferenkeh-Koroma, B Griffiths, M Akil, P Maddison, C Gordon, LS Teh, The LupusQoL and association with demographic and clinical parameters in patients with Systemic Lupus Erythematosus (SLE), J Rheumatol 2010;37:2273-9.<http://www.ncbi.nlm.nih.gov/pubmed/20810500>
   
• K McElhone, J Abbott, LS Teh, Review of Health Related Qualtiy of Life (HRQoL) in patients with Systemic Lupus Erythematosus (SLE),  Lupus 2006;15:633-643.<http://www.ncbi.nlm.nih.gov/pubmed/17120589>
   
• K McElhone, J Abbott, J Shelmerdine, Y Ahmad, I Bruce, C Gordon, K Peers, D Isenberg, A Ferenkeh-Koroma, B Griffiths, M Akil, P Maddison, LS Teh, The Development and Validation of a Disease Specific Quality of Life Measure, the LupusQoL, in Adults with Systemic Lupus Erythematous (SLE), Arthritis Care Res 2007;57:972-979.<http://www.ncbi.nlm.nih.gov/pubmed/17665467>
   
• LS Teh, K McElhone, J Abbott, Chapter on "Health-related quality of life in adults with systemic lupus erythematosus” in Handbook of Disease Burdens and Quality of life measures, VR Preedy, RR Watson (Eds). Springer-Verlag, New York. 2010, Part 3, 3.7, 3261-3279, DOI: 10.1007/978-0-387-78665-0_189
   
• CS Yee, K McElhone, LS Teh, C Gordon, Chapter on “Assessment of disease activity and quality of life in SLE – New Aspects” in Systemic Lupus Erythematosus. Editor-in-Chief AD Woolf. Guest Editors: S Manzi, DA Isenberg. Elsesvier Ltd, Oxford. Best Pract Res Clin Rheumatol 2009, 23:457-67.
   
• M Handa, S McKown, M Gawlicki, Linguistic Validation of the LupusQoL Questionnaire into 13 Languages, Value in Health, Vol. 12, Issue 3, A137, May, 2009.
   
• M Gawlicki, M Handa, S McKown, Linguistic Validation of the LupusQoL Questionnaire into 13 Languages, Presented May 18-19, 2009, ISPOR 14th Annual International Meeting, Orlando, FL, USA. http://corptransinc.com/images/sidebar_pdfs/LupusQol_ISPOR_Orlando09.pdf

• M Jolly, AS Pickard, C Wilke, RA Mikolaitis, L-S Teh, K McElhone, L Fogg, JA Block, Lupus Specific Health Outcome Measure for US Patients: The LupusQoL- US Version©, Ann Rheum Dis 2009;69:29-33. <http://www.ncbi.nlm.nih.gov/pubmed/19126561>

• H Devilliers 1,2, Z Amoura 3,4, JF Besancenot 1, et. al, LupusQoL-FR is valid to assess quality of life in patients with systemic lupus erythematosus. Rheumatology (2012) doi: 10.1093/rheumatology/kes165.
  http://rheumatology.oxfordjournals.org/content/early/2012/07/22/rheumatology.kes165.abstract

• J Yazdany,  Health-related quality of life measurement in systemic lupus erythematosus: The LupusQoL, SLEQoL, and L-QoL, Arthritis Care Res (Hoboken), 2011 November; 63(0 11): S413–S419. 

• F Conti, C Perricone, G Reboldi, M Gawlicki, I Bartosiewicz, VA Pacucci, L Massaro, F Miranda, S Truglia, C Alessandri, FR Spinelli, L-S Teh, F Ceccarelli, G Valesini, Validation of a disease-specific health-related quality of life measure in adult Italian patients with systemic lupus erythematosus: LupusQoL-IT, Lupus, 2014 February 25.

• Meacock R1, Harrison M, McElhone K, Abbott J, Haque S, Bruce I, Teh LS. Mapping the disease-specific LupusQoL to the SF-6D. Qual Life Res. 2014 Dec 16. [Epub ahead of print]

• ON Pamuk, AM Onat, S. Donmez, C Mengüs and B Kisacik.  Validity and reliability of the Lupus QoL index in Turkish systemic lupus erythematosus patients. Lupus (2014) 0, 1-6.

Abstracts relevant to LupusQoL

• 9th International Congress on Systemic Lupus Erythematosus, Vancouver June 2010, EULAR Congress, Rome, June 2010 and 17th Annual ISOQOL Conference, London October 2010. CC Mok, K McElhone, LS Teh. The impact of disease activity and damage on quality of life in systemic lupus erythematosus (SLE) assessed by the LupusQoL questionnaire. Lupus 2010;19 (Suppl): PO2.C.19. 

• 9th International Congress on Systemic Lupus Erythematosus, Vancouver June 2010. Disease specific patient reported outcome benchmarks for US lupus patients: LupusPRO and LupusQoL-US. M Jolly, AS Pickard, K McElhone, LS Teh, RA Mikolaitis, R Rodby, W Sequeira, TO Utset, P Nicassio, M Ishimori, DJ Wallace, MH Weisman, JA Block. Lupus 2010;19 (Suppl):PO.2.C.20.

• 9th International Congress on Systemic Lupus Erythematosus, Vancouver June 2010. Health related quality of life using the LupusQoL-US tool© among systemic lupus erythematosus patients. M Jolly, AS Pickard, LS Teh, K McElhone, C Wilke, RA Mikolaitis, LF Fogg, JA Block. Lupus 2010;19 (Suppl):PO.2.D.42

• 8th European Lupus Meeting, Porto, Portugal April 2011. Structural validity of Chinese LupusQoL – comparison of the Chinese and UK validation cohorts. Mok C C, Ho L Y, Castelino M I, McElhone K, Abbott J, Teh L-S. Lupus 2011:20:P146.

• Rheumatology 2014, Liverpool, UK April, 2014, Trends in the LupusQOL Following Treatment of a Flare in Patients with Systemic Lupus Erythematosus. Kathleen McElhone, Caroline Gordon, Janice Abbott, Chris Sutton, Montana Mullen, Peter Lanyon, Alan Thomas, Alice Muir, Anisur Rahman, David Isenberg, Mary Gayed, Biruk Asfar, Chee-Seng Yee, Robert Stevens, Mohammed Akil, Rachael Kilding, Jayne McDermott, Yasmeen Ahmad, Anne Breslin, Ian Bruce, John Reynolds11, Ben Parker, Sahena Haque, Lee-Suan Teh. 

Communications to scientific meetings and learned societies - relevant to LupusQoL

• 8th International Lupus Meeting, Shanghai, China May 2007, EULAR, Barcelona, June 2007 and American College of Rheumatology AGM, Boston, USA, November 2007. The Relationship between demographic and clinical parameters and Health-Related Quality of Life (HRQoL) in patients with Systemic Lupus Erythematosus (SLE). K McElhone, J Abbott, J Shelmerdine, IN Bruce, Y Ahmad, C Gordon, K Peers, D Isenberg, A Ferenkeh-Koroma, B Griffiths, M Akil, P Maddison, L-S Teh. Lupus 2007;16 (Abstract suppl):PO313,199. Ann Rheum Dis 2007;66 (suppl II):SAT0182,484. Arthritis Rheum 2007;56 (suppl):1918,S734.

• International Society for Quality of Life Research AGM, Toronto, October 2007. M Jolly, SA Pickard, L-S Teh, K McElhone, C Wilke, S Khandelwal, R Rodby, JA Block. Modification and Preliminary Validation of the Lupus Quality of Life (LupusQoL) index for US patients. Qual Life Res 2007;16:A-61#1741.